Leveraging evolution to engineer biology

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We're testing an evolution-based drug discovery model with an iterative loop of computational prediction and experimental validation.

Target identification

Mining billions of years of evolution to systematize target discovery

We integrate across evolutionary scales to identify the causal bases of biological traits.

Model selection

Improving outcomes by picking useful research organisms

We're applying our platform to match disease biology with the most human relevant organisms.

Biologics design

Designing proteins from evolutionary principles

We develop statistical models to predict fitness and function. Our closed loop lets us experimentally test predictions and iterate on our models.

Technology development

Building assays and tools to test our predictions

We're developing and deploying organism-agnostic tools to investigate disease mechanisms.

We publish our work and release open-source tools and resources for the scientific community.

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